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KMID : 1161420160190070615
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Journal of Medicinal Food
2016 Volume.19 No. 7 p.615 ~ p.628
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Antioxidant Activity of Marine Algal Polyphenolic Compounds: A Mechanistic Approach
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Fernando I. P. Shanura
Kim Mi-Sook
Son Kwang-Tae
Jeong Yoon-Hwa
Jeon You-Jin
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Abstract
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Polyphenolic compounds isolated from marine algae exhibit a broad spectrum of beneficial biological properties, including antioxidant, anticancer, antimicrobial, anti-inflammatory, and antidiabetic activities, along with several other bioactivities centered on their antioxidant properties. Consequently, polyphenolic compounds are increasingly being investigated for their potential use in food, cosmetic, and pharmaceutical applications. The antioxidant activities of these compounds have been explored widely through experimental studies. Nonetheless, a theoretical understanding of the structural and electronic properties could broaden research perspectives, leading to the identification and synthesis of efficient structural analogs with prophylactic uses. This review briefly summarizes the current state of knowledge regarding antioxidant polyphenolic compounds in marine algae with an attempt to describe the structure?activity relationship.
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KEYWORD
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flavonoids, halogenated phenolic compounds, phenolic acids, phlorotannins, radical scavenging mechanism, seaweed, ROS
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